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Transient erythroblastopenia of childhood (TEC)

m.c acquired red cell aplasia

 

severe, transient, hypoplastic anemia, mc age 6mo-3yr, usually >12mo age.

Lab

  • reticulocytopenia
  • mod-sev normocytic anemia
  • thrombocytosis
  • normal MCV, HbF, eADA

Treatment

  • virtually all children recover in 1-2 months
  • severe anemia-B.T
    • if >1 transfusion needed, re-evaluate diagnosis
  • No role of corticosteroid

Diamond Blackfan vs TEC

FeatureDBATEC
M:F 1:11:3
Mean age10mo26mo
Hemoglobin (g/dL)1.2-14.8 2.2-12.5
WBCs < 5,000/µL 15% 20%
Platelets >400,000/µL 20% 45%
Adenosine deaminase Increased Normal
MCV increased at diagnosis 80% 5%
MCV increased during recovery 100% 90%
MCV increased in remission100% 0%
HbF increased at diagnosis 100% 20%
HbF increased during recovery 100% 100%
HbF increased in remission 85% 0%
i Antigen increased100% 20%
i Antigen increased during recovery100% 60%
i Antigen increased in remission 90% 0%

Comments

  1. KidsCare Paediatric Neurology CentreMay 29, 2022 at 4:23 AM

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  2. KidsCare Paediatric Neurology CentreMay 29, 2022 at 4:24 AM

    It is really a helpful blog to find some different source to add my knowledge.
    neurology doctor raipur

    ReplyDelete

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